The significance of deposition of immunoglobulin and/or complements at the dermoepidermal junction (DEJ) and civatte bodies in skin lesions of 15 histopathologically confirmed cases of lichen planus (LP) was evaluated. Civatte boides were seen in 6 (40%) patients while in …

Civatte bodies (CBs) are seen as rounded, homogenous, eosinophilic masses on routine H and E staining lying in the deeper parts of epidermis/epithelium and more frequently in dermis/connective tissue. They are known as CBs (in epithelium/epidermis), colloid bodies, or hyaline bodies (in connective tissue). They are 10-25 micrometers in diameter and

A scoop shave biopsy was performed and demonstrated the following histological features: compact hyperkeratosis, epidermal hyperplasia, vertically oriented collagen in the papillary dermis, and civatte bodies near the tips of rete ridges, consistent with hypertrophic lichen planus (Figure 3). Lichen planus (LP) is an acutely occurring inflammatory cutaneous disease frequently with a chronic course. It is characterized by erythematous to deeply purple lichenoid, planar, polygonal papules with thin, translucent and densely adherent scales. Lesions most commonly occur on the skin, oral mucosa and genital areas. 2. The frequency, number and arrangement of civatte bodies in clusters in the papillary dermis as well as multiple immunoglobulins deposition at the civatte bodies on direct immunofluorescence of skin biopsies are important features distinguishing lichen planus from other interface dermatitis. # In lichen planus the basal cells which are shrunken with an eosinophilic cytoplasm and with a pyknotic and fragmented nuclei are called: (MAN -01) a) Tzanck cells b) Civatte bodies Lichen planus(LP) is a chronic inflammatory and immune-mediated disease that affects the skin, nails, hair, and mucous membranes.

A 67-year-old woman with a long-standing history of recurrent dysphagia and esophageal strictures failed to respond to aggressive antireflux management. She required multiple dilations for symptomatic strictures that were discovered throughout the esophagus. Intralesional, topical, and systemic glucocorticoid therapies were utilized without resolution in symptoms. Several years after initial Lichen planus is a skin rash triggered by the immune system.

left forearm, punch biopsy: Lichen planus (see comment) Comment: Sections show acanthosis, hypergranulosis and a lichenoid infiltrate with Civatte bodies.

Nonetheless, … Civatte bodies, also known as colloid bodies or hyaline bodies, are rega rded as a diagnostic hallmark for lichen planus 5 . Historically, they were rst clearly described and illu strated as Civatte bodies - eosinophilic hyaline spherical bodies seen in or just beneath the epidermis, particularly in lichen planus, formed by necrosis of individual basal cells. Synonym (s): colloid bodies.

civatte bodies: anucleate ,necrotic basal cells become incorporated into inflamed papillary dermis -these are civatte bodies or colloid bodies. these are characteristic of lichen planus (but can be found in any chronic dermatitis where basal keratinocytes are injured)

In the absence of a clear diagnosis, their presence is suggestive of disorders characterized by interface dermatitis. Classic lichen planus and lichenoid drug eruption both share similar histopathological features (civatte bodies, wedge shaped hypergranulosis and hyperkeratosis). However, eosinophils favor a lichenoid drug eruption.

Key Words: Apoptosis, civatte bodies, colloid bodies, oral lichen planus, oral lichenoid reaction. Vij H, Vij R, Rao NN, Radhakrishnan R, Gupta V. Quantification of Hyaline bodies, slightly larger than the surroundingepidermalcells,were found in the basal cell layerand alsopres¬ ent in the upper dermis (Fig 1 and 2). These resembled the Civatte bodies of li¬ chen planus. Like Civatte bodies, they were PAS-positive and were particularly well-demonstrated by this stain (color Fig 2). The patientwas Introduction The presence of numerous civatte bodies (CBs) in biopsies is a characteristic finding in skin lesions of patients with various dermatoses, particularly lichen planus (LP) and discoid lupus erythematosus (DLE). In the absence of a clear diagnosis, their presence is suggestive of disorders characterized by interface dermatitis.
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LP has an associated set of characteristic histopathologic findings which include hyperkeratosis, vacuolization of the basal layer, Civatte bodies, wedge-s … bodies (Civatte bodies) seen in or just beneath the epidermis. A Lichen planus (LP) is a specific, relatively common, inflam-matory dermatosis affecting the mucocutaneous surfaces. civatte bodies: anucleate ,necrotic basal cells become incorporated into inflamed papillary dermis -these are civatte bodies or colloid bodies. these are characteristic of lichen planus (but can be found in any chronic dermatitis where basal keratinocytes are injured) Aim: Oral lichen planus and oral lichenoid reaction are familiar keratotic lesions found on the oral mucosa.

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Aim: Oral lichen planus and oral lichenoid reaction are familiar keratotic lesions found on the oral mucosa. Colloid bodies can be microscopically appreciated in both these lesions. The aim of this study was to identify as well as examine the frequency of colloid bodies in oral lichen planus and oral lichenoid reaction by histochemical means.

Br J Oral Maxillofac Surg 2008:46(1):15-21. Figure 3. High-power photograph shows disruption of the junctional zone, with bright pink Civatte bodies (arrow) at the basal zone. Note the inflammatory cells throughout. Figure 1 .